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Table 4 Association between wall area percent and spirometry in all study subjects (n = 154)a

From: Chronic exposure to diesel exhaust may cause small airway wall thickening without lumen narrowing: a quantitative computerized tomography study in Chinese diesel engine testers

Wall area percent Spirometry β SE P
6th generation (%) FEV1 (L/S) −0.011 0.004 0.005
  FVC (L) −0.005 0.004 0.254
  FEV1/FVC (%) −0.147 0.050 0.004
  MMF (L/S) −0.031 0.008 < 0.001
  PEF (L/S) −0.005 0.013 0.709
  FEF25 (L/s) −0.018 0.013 0.168
  FEF50 (L/s) −0.033 0.011 0.003
  FEF75 (L/s) −0.024 0.006 < 0.001
9th generation (%) FEV1 (L/S) −0.006 0.003 0.040
  FVC (L) −0.001 0.003 0.754
  FEV1/FVC (%) −0.110 0.036 0.003
  MMF (L/S) −0.022 0.006 < 0.001
  PEF (L/S) −0.005 0.009 0.639
  FEF25 (L/s) −0.016 0.009 0.094
  FEF50 (L/s) −0.025 0.008 0.002
  FEF75 (L/s) −0.015 0.005 0.001
  1. Definition of abbreviations: FEF25 Forced expiratory flow rate at 25% vital capacity, FEF50 Forced expiratory flow rate at 50% vital capacity, FEF75 Forced expiratory flow rate at 75% vital capacity, FEV1 forced expiratory volume in 1 s, FVC forced vital capacity, L/S liters per second, MMF maximal mid-expiratory flow, PEF peak expiratory flow, SE standard error
  2. a Generalized linear model assessed the associations of spirometry as outcome with average wall area percent with adjustment of age, height, BMI, smoking history. β is calculated per 1% increase in average wall area percent
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