Fig. 5
From: In vitro-in vivo correlations of pulmonary inflammogenicity and genotoxicity of MWCNT
Correlation of the dose-response relationships of the in vivo inflammatory potential in terms of neutrophil influx in mice at day one post-instillation with MWCNT, and the in vitro pro-inflammatory potential in A549 or THP-1a cell mono-cultures exposed in submerged conditions. Dose-response response relationships using mass and surface area are depicted in the top and bottom panels, respectively. The whiskers represent the SEM of the regression estimates based on several doses, and not represented when lower than 0.005