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Fig. 3 | Particle and Fibre Toxicology

Fig. 3

From: Serum peptidome: diagnostic window into pathogenic processes following occupational exposure to carbon nanomaterials

Fig. 3

Discriminant peptide ranking for biomarker model refinement. PLS-DA was employed to select the most predictive peptide measures that a resolved High CNT/F and Low CNT/F exposure groups. b The rank of each peptide measure’s contribution to the PLS-DA model was provided by the weighted sum to the squared correlation as a VIP score (peptide measures shown by their unique index identifier). Using an accepted 1.0 VIP cutoff, 41 peptide measures were found most discriminatory between groups. c Box plot of the top five scoring peptide measures between High and Low CNT/F exposure groups

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Particle and Fibre Toxicology

ISSN: 1743-8977

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