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Table 1 CNT/F worker demographics, exposure, and SCIP metrics for low and high exposure groups

From: Serum peptidome: diagnostic window into pathogenic processes following occupational exposure to carbon nanomaterials

Worker demographics and exposure metric data

Exposure groups

High

Low

Demographics

Age [binned 1–5]a, \({\bar{\text{x}}}\)̄ (SE)

3.0 (0.4)

3.0 (0.3)

Sex, # Females, n (%)

3 (25)

2 (17)

Education [binned 1–4]b, \({\bar{\text{x}}}\)̄ (SE)

2.8 (0.4)

3.2 (0.3)

Former Smokers, n (%)

3 (25)

2 (17)

Allergies, n (%)

5 (42)

5 (42)

Hypertension, n (%)

3 (25)

2 (17)

Current solvent Exp., n (%)

7 (58)

6 (50)

Past solvent Exp., n (%)

6 (50)

5 (42)

CNT/F exp

Inhalable EC [µg/m3], \({\bar{\text{x}}}\)̄ (SE)

8.706 (5.402)

0.055 (0.014)

Respirable EC [µg/m3], \({\bar{\text{x}}}\)̄ (SE)

1.564 (0.964)

0.017 (0.006)

CNT/F structure Count [s/cm3], \({\bar{\text{x}}}\)Ì„ (SE)

0.442 (0.310)

0.005 (0.002)

CNT/F duration [binned 1–5]c, \({\bar{\text{x}}}\)̄ (Se)

3.3 (0.3)

2.4 (0.4)

SCIP assay

IL6 log fold-change, \({\bar{\text{x}}}\)Ì„ (SE)

0.958 (0.094)

0.980 (0.069)

CCL2 log fold-change, \({\bar{\text{x}}}\)Ì„ (SE)

0.830 (0.077)

1.001 (0.099)

TNFalpha log fold-change, \({\bar{\text{x}}}\)Ì„ (SE)

1.231 (0.187)

0.950 (0.102)

VCAM log fold-change, \({\bar{\text{x}}}\)Ì„ (SE)

1.159 (0.178)

1.154 (0.141)

ICAM log fold-change, \({\bar{\text{x}}}\)Ì„ (SE)

0.907 (0.128)

1.228 (0.247)

  1. \({\bar{\text{x}}}\)Ì„, mean; SE, standard error; n, sample size; EC, elemental carbon; CNT/F, carbon nanotubes and nanofibers; SCIP, serum cumulative inflammatory potential
  2. aAge binning (years): 1 (< 25), 2 (25- < 35), 3 (35- < 45), 4 (45- < 55), 5 (55- < 65)
  3. bEducation binning: 1 (high/trade school), 2 (some college), 3 (college grad), 4 (postgraduate)
  4. cCNT/F exposure duration binning (years): 1 (0), 2 (0.01- < 1), 3 (1- < 5), 4 (5- < 10), 5 (≥ 10)