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Fig. 5 | Particle and Fibre Toxicology

Fig. 5

From: Exposure to environmentally relevant concentrations of ambient fine particulate matter (PM2.5) depletes the ovarian follicle reserve and causes sex-dependent cardiovascular changes in apolipoprotein E null mice

Fig. 5

Effects of ovariectomy and PM2.5-exposure on atherosclerosis. A Representative images of atherosclerotic plaques in Air- and PM2.5-exposed and ovariectomized (OVAX) and ovary intact (Sham) mice. Cross-sections of aortic root were stained with the lipid stain Oil Red O and counterstained with hematoxylin. Scale bar 1.5 mm for all four aortic root cross-sections. Areas within rectangles are magnified in insets. B Means ± SEM percentages of Oil Red O-positive endothelial cell area. ns, no significant difference among Sham PM2.5, OVAX Air, and OVAX PM2.5; all three groups differed significantly (P < 0.05) from Sham Air. N = 3–4/group

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Particle and Fibre Toxicology

ISSN: 1743-8977

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