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Table 7 Percent change from baseline ± SEM in heart rate variability measures during weeks 6–11 in male and female ApoE-/- mice, 2017 cohort

From: Exposure to environmentally relevant concentrations of ambient fine particulate matter (PM2.5) depletes the ovarian follicle reserve and causes sex-dependent cardiovascular changes in apolipoprotein E null mice

 

Male

Female

Air

PM2.5

p-value

Air

PM2.5

P-value

HR

% change

2.3 ± 0.7

1.6 ± 0.5

0.396

7.1 ± 0.7

7.5 ± 1.3

0.786

SDNN

% change

3.2 ± 2.4

1.5 ± 1.4

0.527

-2.8 ± 2.2

-12.5 ± 2.3

0.002

RMSSD

% change

12.7 ± 3.8

-3.6 ± 2.5

 < 0.001

17.4 ± 8.1

-12.5 ± 2.1

0.001

  1. P-values are for PM2.5 versus Air of same sex and BP measurement method, t-test
  2. HR, heart rate; SDNN, standard deviation of normal RR intervals; RMSSD, root mean squared of successive differences of normal RR intervals
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Particle and Fibre Toxicology

ISSN: 1743-8977

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