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Table 8 Percent change from baseline ± SEM in heart rate variability measures during weeks 6–11 in OVAX and SHAM female ApoE-/- mice, 2018 cohort

From: Exposure to environmentally relevant concentrations of ambient fine particulate matter (PM2.5) depletes the ovarian follicle reserve and causes sex-dependent cardiovascular changes in apolipoprotein E null mice

 

OVAX

SHAM

Air

PM2.5

P-value

Air

PM2.5

P-value

HR

% change

2.6 ± 0.5

3.6 ± 0.5

0.046

2.8 ± 0.5

4.9 ± 0.5

 < 0.001

SDNN

% change

− 4.6 ± 1.3

− 5.0 ± 1.2

0.142

2.8 ± 1.4

− 1.1 ± 1.4

0.134

RMSSD

% change

− 2.9 ± 1.5

2.0 ± 1.6

0.027

− 8.3 ± 2.7

− 0.9 ± 1.7

0.285

  1. P-values are for PM2.5 versus Air of same group, t-test
  2. HR, heart rate; SDNN, standard deviation of normal RR intervals; RMSSD, root mean squared of successive differences of normal RR intervals
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Particle and Fibre Toxicology

ISSN: 1743-8977

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