Fig. 6

Exposure to inhaled DEP and high-fat diet alters circulating cytokine and chemokines. Mean concentration for circulating inflammatory factors: A IL-1α, B IL-3, C IL-13, D IL-15, E G-CSF, F LIF, G MIP-2, H RANTES, and I TNF-α measured in plasma in C57Bl/6 male mice exposed to inhaled diesel exhaust particles (DEP- 35 μg PM) or saline control (CON) twice a week for four weeks on either low-fat (LF) or high-fat (HF) diet. Data are depicted as ± SEM with *p < 0.05 compared to LF + CON, †p < 0.05 compared to LF + DEP, ‡p < 0.05 compared to HF + CON, #p < 0.07 compared to LF + CON, and ◦p < 0.06 compared to LF + DEP by two-way ANOVA