Fig. 1
From: Chronic effects of two rutile TiO2 nanomaterials in human intestinal and hepatic cell lines
TEM images of differentiated Caco-2 cross sections showing the uptake of NM-103 (A, C, E, G, I) and NM-104 (B, D, F, G, J) exposed to 50 (A–D) or 12.5 µg/cm2 (E–H). NM aggregates in cell cytoplasm increase over time. Differentiated Caco-2 cells were treated for 24 h (A, B), 24 h with a 1-week recovery period (C, D), 1 week (E, F), 1 week with a 1-week recovery period (G, H), or 2 weeks (I, J). NMs were seen close to the nucleus deforming the core (full arrows)