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Fig. 3 | Particle and Fibre Toxicology

Fig. 3

From: Aluminium oxide nanoparticles compromise spatial memory performance and proBDNF-mediated neuronal function in the hippocampus of rats

Fig. 3

Effects of aluminaNP on neuronal function in the hippocampal slices. A Input–output synaptic function. B Characteristic time courses of fEPSP slope. The bidirectional arrow indicated the application of LFS. C Time coursing changes in fEPSPs slope. The magnitude of LTD was determined as responses between 41 and 60 min after LFS. D A typical consecutive sample trace of NMDA-GluN2B EPSC from each group (left) and the frequency of NMDA-GluN2B EPSCs (right). E The amplitude of NMDA-GluN2B EPSCs. The levels of F superoxide anion radical and G hydroxyl free radical in the homogenates of hippocampal slices. Data are presented as mean ± SEM. *, P < 0.05, versus other groups. The number of rats in each group was indicated in each legend

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