Table 1 Ambient concentrations of selected PAHs in PM2.5 and their BaP-TEQs and contributions of PAHs to BaP-TEQs based on relative potencies (REPs) determined in AhR-CALUX and AZ-AhR assays
Compound | Abbreviation | PAH concentrations in PM2.5 (ng/m3) | ToxCast human HepG2-based AhR-CALUX cells | Human HepG2-AZ-AhR cells | ||||
|---|---|---|---|---|---|---|---|---|
REPa | BaP-TEQs (ng/m3)b | Contribution of PAHs to total BaP-TEQ (%) | REPc | BaP-TEQs (ng/m3)b | Contribution of PAHs to total BaP-TEQ (%) | |||
Benz(a)anthracene | BaA | 0.07 ± 0.02 | 0.29 | 0.02 ± 0.01 | 0.08 ± 0.03 | 0.60 | 0.04 ± 0.01 | 0.63 ± 0.19 |
Chrysene | CHR | 0.19 ± 0.04 | 0.34 | 0.07 ± 0.01 | 0.24 ± 0.08 | 1.50 | 0.29 ± 0.06 | 4.09 ± 1.21 |
Benzo(b)fluoranthene | BbF | 0.30 ± 0.08 | 5.44 | 1.63 ± 0.42 | 5.83 ± 2.00 | 4.00 | 1.19 ± 0.32 | 16.61 ± 4.85 |
Benzo(k)fluoranthene | BkF | 0.12 ± 0.03 | 213.39 | 25.81 ± 7.41 | 86.52 ± 3.87 | 43.20 | 5.23 ± 1.52 | 69.61 ± 6.87 |
Benz(e)pyrene | BeP | 0.22 ± 0.06 | 2.02 | 0.44 ± 0.13 | 1.57 ± 0.60 | NA | – | – |
Benzo(a)pyrene | BaP | 0.13 ± 0.03 | 1.00 | 0.13 ± 0.03 | 0.47 ± 0.17 | 1.00 | 0.13 ± 0.03 | 1.85 ± 0.59 |
Dibenz(a,h)anthracene | D(a,h)A | 0.03 ± 0.01 | 49.45 | 1.49 ± 0.51 | 5.29 ± 2.16 | 17.20 | 0.52 ± 0.18 | 7.22 ± 2.71 |
Total | 1.07 ± 0.25 | – | 29.59 ± 7.45 | 100 | – | 7.41 ± 1.57 | 100 | |