Fig. 6
Lung burden and correlation between lung burden and relative lung weights and BALF markers. Lung burden of TiO2 NPs in male (A) and female (B) rats was measured by a Zeeman atomic absorption spectrometry (n = 10). Correlation between lung burden and relative lung weight (C, D), LDH activity in the BALF (E, F), and neutrophil number in the BALF (G, H) was analyzed using the Pearson’s correlation coefficients, and are shown by sex (male: C, E and G; female: D, F and H) (C and D: n = 10/each group, total n = 40, E–H: n = 5/each group, total n = 20). r: Pearson’s correlation coefficient. Abbreviation: N.T., not tested