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Fig. 3 | Particle and Fibre Toxicology

Fig. 3

From: Grouping of orally ingested silica nanomaterials via use of an integrated approach to testing and assessment to streamline risk assessment

Fig. 3

A Dissolution half-time (t1/2) of the selected silica panel (1 mg) measured in PSF fluids. Data are expressed in hours and as mean ± standard deviation (n = 3). **p < 0.01, ***p < 0.001 and ****p < 0.0001 versus both NM-200 and NM-203 B Similarity assessment by BF pairwise analysis for selected NFs (value are scaled between 0 and 1) based on NF dissolution rate (ratio between rate ‘dissolved’ of one NF by the other) together with the half-time values in PSF fluids. BF Values close to zero (blue color) indicate that the NFs are not similar and BF values close to one (red color) indicate similarity between NFs

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