Fig. 7

Aggravation of movement disorder after ischemic stroke elicited by PM2.5 collected at Yokohama, Japan. PM2.5 collected at Yokohama, Japan was suspended in water and was intranasally (i.n.) administered at a dose of 100 µg/mouse once a day for 7 days. Coordinated movement was measured by a rotarod test before (day 0) and 1, 3, 5 and 7 days after photothrombosis induction. The reported values are the mean ± S.D. (n = 7 animals in each group). The area under the curve (AUC) from 1 to 7 days was calculated, and the AUC was analyzed using Student’s t test. The p value of the vehicle versus 100 µg PM2.5 groups was 0.0013