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Fig. 7 | Particle and Fibre Toxicology

Fig. 7

From: Derivation of first-order dissolution rates to estimate particle clearance and burden in the human respiratory tract

Fig. 7

Effect of inhaled particle size (moderately soluble, dissolution rate of 1 × 10−6 g/cm2 per day; density of 3 g/cm3) on alveolar burden (Panel A) and daily dissolution from pulmonary and interstitial/lymph compartments (Panel B). Monodisperse aerosol (concentration = 1.0 µg/m3) of indicated sized particles were inhaled for 8-h per day by an adult male exposed while sitting at rest

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