Fig. 5From: Single inhalation exposure to polyamide micro and nanoplastic particles impairs vascular dilation without generating pulmonary inflammation in virgin female Sprague Dawley ratsVascular reactivity in the radial artery was assessed by establishing drug response curves with the endothelial-dependent vasodilator, methacholine (A), the endothelial independent-vasodilator, sodium nitroprusside (B), and the vasoconstrictor, phenylephrine (C). Significance was assessed by comparing overall reactivity via a four-parameter nonlinear regression analysis. Data are presented as mean ± SEM, n = 7–9, *Significantly different (p < 0.05) from filtered air controlsBack to article page