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Fig. 5 | Particle and Fibre Toxicology

Fig. 5

From: Single inhalation exposure to polyamide micro and nanoplastic particles impairs vascular dilation without generating pulmonary inflammation in virgin female Sprague Dawley rats

Fig. 5

Vascular reactivity in the radial artery was assessed by establishing drug response curves with the endothelial-dependent vasodilator, methacholine (A), the endothelial independent-vasodilator, sodium nitroprusside (B), and the vasoconstrictor, phenylephrine (C). Significance was assessed by comparing overall reactivity via a four-parameter nonlinear regression analysis. Data are presented as mean ± SEM, n = 7–9, *Significantly different (p < 0.05) from filtered air controls

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