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Fig. 1 | Particle and Fibre Toxicology

Fig. 1

From: Human dendritic cell maturation induced by amorphous silica nanoparticles is Syk-dependent and triggered by lipid raft aggregation

Fig. 1

Syk controls moDC phenotype in response to SAS-NPs. Immature moDCs were pre-treated for 1 h with Syk inhibitor IV (1 μM) and then treated for 16 h with SAS-NPs (12.5 or 25 μg.mL−1). Cells were then collected, washed, and analyzed by flow cytometry for surface marker expression. Results are expressed as relative fluorescence intensity (RFI) compared with non-stimulated cells and represented as the mean ± SEM of 3 independent experiments. *p < 0.05; **p < 0.01 One-way Anova, Kruskal–Wallis test

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