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Fig. 3 | Particle and Fibre Toxicology

Fig. 3

From: Human dendritic cell maturation induced by amorphous silica nanoparticles is Syk-dependent and triggered by lipid raft aggregation

Fig. 3

Syk is phosphorylated in response to SAS-NPs. Immature moDCs were treated for 30, 60, 90 and 120 min with SAS-NPs (12.5 or 25 μg.mL−1). Immunoblotting of whole-cell extracts was used to quantify the phosphorylated form of Syk. A Representative experiment. B Results of 3 independent experiments are represented. Bands were quantified using the Image Lab software. Results are expressed as the fold induction, representing the ratio of the normalised intensity of specific bands of treated cells divided by the normalised intensity of bands of untreated cells (pSyk/Syk). *p < 0.05 One-way Anova, Kruskal–Wallis test

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