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Fig. 4 | Particle and Fibre Toxicology

Fig. 4

From: Uncovering the Fate and Risks of Intravenously Injected Prussian Blue Nanoparticles in mice by an Integrated Methodology of Toxicology, Pharmacokinetics, Proteomics, and Metabolomics

Fig. 4

Proteomics and Metabolomics analysis of mouse lungs after i.v. administration of 20 mg/kg PB NPs. (a) Venn diagram of the differentially expressed proteins in the lungs. (Blue: 7th day, Pink: 60th day). (b-c) KEGG pathway enrichment analysis of differentially expressed proteins in the lungs on the 7th day (b) and the 60th day (c). (d) OPLS-DA score plot of lung metabolomics. (e) Venn diagram of the changed metabolites in the lungs (blue: 7th day, pink: 60th day). (f-g) KEGG pathway enrichment analysis of the changed metabolites in the lungs on the 7th day (f) and the 60th day (g)

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Particle and Fibre Toxicology

ISSN: 1743-8977

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