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Fig. 14 | Particle and Fibre Toxicology

Fig. 14

From: MMP-3-mediated cleavage of OPN is involved in copper oxide nanoparticle-induced activation of fibroblasts

Fig. 14

Schematic diagram of potential mechanisms of Nano-CuO-induced activation of fibroblasts. Exposure of lung epithelial BEAS-2B cells and U937* macrophages to Nano-CuO caused increased expression and activity of MMP-3 and increased production of MMP-3-cleaved OPN, leading to the activation of fibroblasts. Graphics were created with BioRender (https://BioRender.com)

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Particle and Fibre Toxicology

ISSN: 1743-8977

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