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Fig. 2 | Particle and Fibre Toxicology

Fig. 2

From: Oral intake of titanium dioxide nanoparticles affect the course and prognosis of ulcerative colitis in mice: involvement of the ROS-TXNIP-NLRP3 inflammasome pathway

Fig. 2

Change of mice colitis activity after treatment with TiO2 NPs. Change of body weight of mice in the experiment of UC developing (a) and UC self-healing (b), and change of the DAI score in the experiment of UC developing (c) and UC self-healing (d) (n = 10, \(\overline{x }\)±s). *p < 0.05, **p < 0.01, compared with CT group; ΔP < 0.05, ΔΔP < 0.01, compared with DSS group. The CMDI score (e, n = 10), colonic length (f, n = 10), colonic mucosal thickness (g, n = 3), and colonic histopathological score (h, n = 3) in the experiment of UC developing and UC self-healing (\(\overline{x }\) ± s). *p < 0.05, **p < 0.01, compared with CT group; ΔP < 0.05, ΔΔP < 0.01, comparison between two groups

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