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Fig. 7 | Particle and Fibre Toxicology

Fig. 7

From: Role of the protease-activated receptor-2 (PAR2) in the exacerbation of house dust mite-induced murine allergic lung disease by multi-walled carbon nanotubes

Fig. 7

Hypothetical illustration showing PAR2-independent and PAR2-dependent components of allergic lung disease in mice caused by co-exposure to MWCNTs and HDM allergens. MWCNTs enhance HDM allergen-induced eosinophilic inflammation through a STAT6-dependent mechanism that does not involve PAR2. However, PAR2 is postulated to promote airway fibrogenesis by increasing the expression of ARG-1

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Particle and Fibre Toxicology

ISSN: 1743-8977

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