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Fig. 2 | Particle and Fibre Toxicology

Fig. 2

From: A 90-day oral exposure to food-grade gold at relevant human doses impacts the gut microbiota and the local immune system in a sex-dependent manner in mice

Fig. 2

Feed intake and body weight of mice exposed to Ref-Au or E175 for 13 weeks. A Daily feed intake of male mice exposed for 13 weeks to Ref-Au at 10 µg/kg BW/d or E175 at 0.1, 1 and 10 µg/kg BW/d incorporated in food pellets. B Body weight of male mice orally exposed for 13 weeks to Ref-Au at 10 µg/kg BW/d or E175 at 0.1, 1 and 10 µg/kg BW/d. C Daily feed intake of female mice exposed for 13 weeks to Ref-Au at 10 µg/kg BW/d or E175 at 0.1, 1 and 10 µg/kg BW/d incorporated in food pellets. D Body weight of female mice orally exposed for 13 weeks to Ref-Au at 10 µg/kg BW/d or E175 at 0.1, 1 and 10 µg/kg BW/d. For statistical comparisons, the dagger (†) indicates Ref-Au versus control, asterisk (*) indicates E175 0.1 µg/kg BW/d versus control, and double dagger (‡) indicates E175 1 µg/kg BW/d versus control. Data are expressed as the mean ± SEM. P < 0.05; *P < 0.05; ***P < 0.001; ‡‡‡P < 0.001; two-way ANOVA and post hoc Tukey’s test

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