Table 1 Body and organ weights in mice exposed to Ref-Au or E175 for 13 weeks
Sex | Group | Body weight at sacrifice (g) | Body weight gain at sacrifice (%) | Liver (g) | Spleen (mg) |
|---|---|---|---|---|---|
Male | Control | 31.7 ± 0.8 | 49.7 ± 2.4 | 1.43 ± 0.04 | 81.16 ± 3.50 |
Ref-Au 10 µg/kg BW/d | 31.9 ± 0.7 | 52.2 ± 2.8 | 1.48 ± 0.05 | 95.55 ± 6.81 | |
E175 0.1 µg/kg BW/d | 30.5 ± 0.7 | 44.7 ± 2.5 | 1.40 ± 0.06 | 78.00 ± 3.08 | |
E175 1 µg/kg BW/d | 29.3 ± 0.6 | 44.6 ± 1.9 | 1.37 ± 0.05 | 75.84 ± 1.63 | |
E175 10 µg/kg BW/d | 30.9 ± 0.8 | 47.8 ± 3.1 | 1.38 ± 0.04 | 74.50 ± 2.51 | |
Female | Control | 22.7 ± 0.3 | 38.3 ± 1.6 | 1.03 ± 0.02 | 84.18 ± 3.55 |
Ref-Au 10 µg/kg BW/d | 23.1 ± 0.2 | 41.2 ± 1.6 | 1.06 ± 0.02 | 81.60 ± 2.91 | |
E175 0.1 µg/kg BW/d | 22.3 ± 0.2 | 38.4 ± 2.4 | 1.04 ± 0.04 | 81.91 ± 4.50 | |
E175 1 µg/kg BW/d | 22.2 ± 0.2 | 34.5 ± 2 | 1.05 ± 0.02 | 76.58 ± 2.81 | |
E175 10 µg/kg BW/d | 22.2 ± 0.3 | 32.5 ± 1.8 | 1.01 ± 0.02 | 82.47 ± 2.22 |