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Fig. 6 | Particle and Fibre Toxicology

Fig. 6

From: Long-term PM2.5 exposure disrupts corneal epithelial homeostasis by impairing limbal stem/progenitor cells in humans and rat models

Fig. 6

The circadian rhythm was involved in the activation and dysregulation of LSPCs. (A-I) The expression of circadian rhythm-related genes in PBS and PM2.5 group at 2 days or 3 weeks. N = 3 in each group. *p < 0.05, **p < 0.01, ***p < 0.001. (J) H2O2 in rat tears was elevated at 2 days in the PM2.5 group and was lower than the control group after 3 weeks. N = 6 in each group. **p < 0.01. PBS: the PBS eyedrop administration group; PM: the PM2.5 eyedrop administration group; LSPCs: Limbal stem/progenitor cells; H2O2: hydrogen peroxide

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Particle and Fibre Toxicology

ISSN: 1743-8977

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