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Fig. 3 | Particle and Fibre Toxicology

Fig. 3

From: Single-cell transcriptome sequencing–based analysis: probing the mechanisms of glycoprotein NMB regulation of epithelial cells involved in silicosis

Fig. 3

Screening of key molecules involved in the occurrence of EMT phenomenon in alveolar II epithelial cells. A. Venn diagram showing the differential genes for the three subtypes of AT2 (*P < 0.05, avg_logFC > 1.0). B. Sankey diagram showing the function of 18 differential genes. C. Venn diagram showing the differential genes for the three subtypes of AT2. D. Violin plot showing the expression of Gpnmb in AT2. E. t-SNE plot showing the distribution of the two subtypes of AT2, Gpnmb+AT2, and Gpnmb−AT2.F. Pie chart showing the percentage of each AT2 subtype occupying the total number of AT2 cells. G. GO enrichment analysis of the top 20 differential genes

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Particle and Fibre Toxicology

ISSN: 1743-8977

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