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Fig. 2 | Particle and Fibre Toxicology

Fig. 2

From: Amorphous silica nanoparticles cause abnormal cytokinesis and multinucleation through dysfunction of the centralspindlin complex and microfilaments

Fig. 2

Intracellular distribution of aSiNPs and their effect on the structure and distribution of microfilaments (green: microfilament, blue: nucleus, red: fluorescent silica nanoparticles). (A) Immunofluorescence images of L-02 cells in control group, (a) nucleus transverse section, (b) cell upper surface transverse section. (B) and (C) Immunofluorescence images of L-02 cells in aSiNPs treated group (20 µg/ml), (a) nucleus transverse section, (b) cell upper surface transverse section. Yellow arrow head: a multinucleated cell induced by aSiNPs. White arrow heads: agglomerated microfilaments and the co-localized aSiNPs.

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Particle and Fibre Toxicology

ISSN: 1743-8977

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