Skip to main content
Fig. 5 | Particle and Fibre Toxicology

Fig. 5

From: Amorphous silica nanoparticles cause abnormal cytokinesis and multinucleation through dysfunction of the centralspindlin complex and microfilaments

Fig. 5

Effects of aSiNPs (20 µg/ml) on the localizations of Aurora B, MKLP1, and CYK4 on midbody during cytokinesis. (A) Abnormal co-localization of Aurora B and MKLP1 on midbody (white: microtubule, red: Aurora B, green: MKLP1), (a) normal co-localization of Aurora B and MKLP1 on midbody in control group, (b) lack of MKLP1 on midbody in aSiNPs treated group, (c) incorrect localization of Aurora B and MKLP1 on midbody in aSiNPs treated group. Yellow arrow heads: Aurora B and MKLP1 on midbody. (B) Abnormal co-localization of MKLP1 and CYK4 on midbody (white: microtubule, green: MKLP1, red: CYK4), (a) normal co-localization of MKLP1 and CYK4 on midbody in control group, (b) lack of CYK4 on midbody in aSiNPs treated group, (c) incorrect localization of MKLP1 and CYK4 on midbody in aSiNPs treated group. White arrow heads: MKLP1 and CYK4 on midbody

Back to article page

Particle and Fibre Toxicology

ISSN: 1743-8977

Contact us