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Fig. 3 | Particle and Fibre Toxicology

Fig. 3

From: Effect of sp3/sp2 carbon ratio and hydrodynamic size on the biodistribution kinetics of nanodiamonds in mice via intravenous injection

Fig. 3

Time-course organ distribution pattern of NDs in the major accumulating organs. (a) The combined ND levels in the liver, spleen, and lung show constant levels from day 1 to day 28. (b) The ND levels in the liver show saturation levels of about 50–70% of the initial dose (ID) from day 1 to day 28. (c) The ND levels in the spleen show an increasing pattern up to day 28. (d) The ND levels in the lung show a decreasing pattern from 30 min post-injection (57% ID) to day 28 (27% ID). Data are expressed as mean ± SEM (n = 5) for each group

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Particle and Fibre Toxicology

ISSN: 1743-8977

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