Fig. 4

Representative dark-field and bright-field images of the liver, spleen, and lung at day 7 post-injection of ^lowND. Liver section of mice in the (a, b) vehicle control (VEH) group and (c, d) ^lowND group. Spleen section of mice in the (e, f) VEH group and (g, h) ^lowND group. Lung section of mice in the (i, j) VEH group and (k, l) ^lowND group. The red arrows in the insert image of Fig. 4d, h, and i show that the NDs were located in the liver sinusoids (engulfed by Kupffer cells), red pulps in the spleen, and capillaries in the lungs. The dark-field and bright-field images were taken from the same slides. Scale bar = 100 μm