Fig. 9
Diagram of the effects of sp3/sp2 carbon ratio and hydrodynamic size on the biokinetics of NDs injected into the tail vein of mice. No correlation of sp3/sp2 carbon ratio with the organ distribution levels was observed, suggesting that sp3 and sp2 carbon has no difference in the biokinetics of carbon particles. However, the hydrodynamic size showed excellent correlations with the major accumulating organs such as liver, spleen, and lungs, which suggests that hydrodynamic size is one of the major factors deciding the biokinetics of NDs