Table 3 Cellular components in the PLF at week 104 of the experimental period
Test article | Total dose (mg/kg) | Male | ||||||
|---|---|---|---|---|---|---|---|---|
WBC (× 102/µL) | Leukocytes, differential | |||||||
Lymphocytes | Neutrophils | Eosinophils | Basophils | Monocytes | ||||
(× 102/µL) | (× 102/µL) | (× 102/µL) | (× 102/µL) | (× 102/µL) | ||||
Nontreatment | – | (5) | 46.6 ± 6.6 | 6.4 ± 2.0 | 1.4 ± 0.7 | 0.5 ± 0.6 | 0.0 ± 0.0 | 38.2 ± 6.3 |
Control | 0 | (5) | 71.2 ± 48.0 | 11.6 ± 9.5 | 2.7 ± 1.6 | 1.9 ± 2.9 | 0.0 ± 0.0 | 54.9 ± 35.9 |
MWNT-7 | 0.128 | (5) | 55.1 ± 8.8 | 5.0 ± 1.1 | 2.2 ± 0.6 | 1.7 ± 0.7 | 0.0 ± 0.0 | 46.1 ± 7.8 |
MWNT-7 | 0.64 | (5) | 69.7 ± 7.5 | 3.2 ± 0.7# | 2.0 ± 0.6 | 2.7 ± 1.2 | 0.0 ± 0.0 | 61.8 ± 6.7 |
MWNT-7 | 3.2 | (1) | 103.0 | 10.4 | 8.0 | 1.4 | 0.0 | 83.2 |
VGCF™-H | 0.128 | (5) | 43.0 ± 14.5 | 9.8 ± 5.3 | 1.2 ± 0.4 | 0.2 ± 0.2 | 0.0 ± 0.0 | 31.8 ± 11.4 |
VGCF™-H | 0.64 | (5) | 44.4 ± 5.0 | 4.8 ± 1.6 | 1.4 ± 0.4 | 0.5 ± 0.3 | 0.0 ± 0.0 | 37.7 ± 3.4 |
VGCF™-H | 3.2 | (5) | 56.0 ± 5.7 | 6.7 ± 1.8 | 1.9 ± 0.3 | 1.1 ± 0.4 | 0.0 ± 0.0 | 46.2 ± 4.8 |
Test article | Total dose (mg/kg) | Female | ||||||
|---|---|---|---|---|---|---|---|---|
WBC (× 102/µL) | Leukocytes, differential | |||||||
Lymphocytes | Neutrophils | Eosinophils | Basophils | Monocytes | ||||
(× 102/µL) | (× 102/µL) | (× 102/µL) | (× 102/µL) | (× 102/µL) | ||||
Nontreatment | – | (5) | 28.9 ± 14.1 | 4.7 ± 3.3 | 0.7 ± 0.5 | 0.3 ± 0.2 | 0.0 ± 0.0 | 23.3 ± 10.5 |
Control | 0 | (5) | 36.9 ± 13.1 | 7.0 ± 4.2 | 1.0 ± 0.3 | 0.4 ± 0.2 | 0.0 ± 0.0 | 28.6 ± 8.9 |
MWNT-7 | 0.128 | (5) | 34.4 ± 10.8 | 5.8 ± 6.1 | 0.7 ± 0.4 | 1.1 ± 0.7 | 0.0 ± 0.0 | 26.8 ± 8.5 |
MWNT-7 | 0.64 | (5) | 39.7 ± 8.8 | 4.4 ± 3.7 | 1.1 ± 1.0 | 1.6 ± 1.8 | 0.0 ± 0.0 | 32.6 ± 8.8 |
MWNT-7 | 3.2 | (5) | 61.9 ± 32.8 | 5.6 ± 6.8 | 1.3 ± 0.8 | 0.7 ± 0.4 | 0.0 ± 0.0 | 54.4 ± 25.7 |
VGCF™-H | 0.128 | (5) | 29.1 ± 7.2 | 4.5 ± 2.9 | 0.6 ± 0.4 | 0.1 ± 0.2 | 0.0 ± 0.0 | 23.9 ± 4.2 |
VGCF™-H | 0.64 | (5) | 31.8 ± 9.4 | 6.0 ± 5.8 | 0.6 ± 0.4 | 0.3 ± 0.3 | 0.0 ± 0.0 | 24.9 ± 5.3 |
VGCF™-H | 3.2 | (5) | 42.7 ± 7.2 | 6.9 ± 3.4 | 0.7 ± 0.3 | 0.4 ± 0.2 | 0.0 ± 0.0 | 34.7 ± 4.1 |