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Table 5 Clinical chemistry in the PLF at week 104 of the experimental period

From: Difference in carcinogenicities of two different vapor grown carbon fibers with different physicochemical characteristics induced by intratracheal instillation in rats

Test article

Total dose

Male

Female

(mg/kg)

 

LDH

μ-TP

μ-ALB

 

LDH

μ-TP

μ-ALB

 

(U/L)

(mg/dL)

(µg/mL)

 

(U/L)

(mg/dL)

(µg/mL)

Nontreatment

(5)

9 ± 2

38.8 ± 8.9

81.3 ± 20.3

(5)

6 ± 4

48.5 ± 16.7

115.4 ± 35.7

Control

0

(5)

19 ± 20

66.5 ± 41.4

131.2 ± 62.4

(5)

5 ± 2

43.3 ± 7.2

103.7 ± 16.8

MWNT-7

0.128

(5)

11 ± 2

62.0 ± 29.0

117.4 ± 42.0

(5)

5 ± 1

46.8 ± 16.7

112.9 ± 38.8

MWNT-7

0.64

(5)

23 ± 17

59.6 ± 21.7

103.0 ± 18.1

(5)

8 ± 4

49.2 ± 29.6

106.2 ± 62.5

MWNT-7

3.2

(1)

46

257.1

307.3

(5)

32 ± 40

136.4 ± 129.8

192.0 ± 114.9

VGCF™-H

0.128

(5)

8 ± 2

40.4 ± 14.3

92.9 ± 27.6

(5)

6 ± 2

44.4 ± 21.7

105.0 ± 47.3

VGCF™-H

0.64

(5)

13 ± 9

58.1 ± 19.4

116.8 ± 26.4

(5)

11 ± 15

51.5 ± 20.7

118.8 ± 33.1

VGCF™-H

3.2

(5)

13 ± 6

81.8 ± 64.0

145.9 ± 63.3

(5)

10 ± 6

61.7 ± 25.5

142.3 ± 54.1

  1. There was no significant difference between groups
  2. Number in parentheses indicates the number of animals examined
  3. The values indicate as mean ± S.D