The subacute toxicity and underlying mechanisms of biomimetic mesoporous polydopamine nanoparticles

Table 1 The amount of PDA given in previous studies

PDA dosage	Drug dosage	Feeding ratio of drug and PDA	Mice bodyweight	Amount of PDA	References
10 mg/kg			15–17 g	0.15–0.17 mg	[15]
12 mg/kg			18–20 g	0.22–0.24 mg	[16]
	5 mg/kg	0.25:1 (w:w)	16 g	0.32 mg	[17]
	5 mg/kg	1:2.5 (w:w)		0.25 mg per 20 g bodyweight	[18, 19]
	10 mg/kg	1:5 (w:w)	25 g	1.25 mg	[20]
	10 mg/kg	0.25:1, 0.5:1, 1:1 and 2:1 (w:w)		0.8 mg per 20 g bodyweight	[21]
	2.5 mg/kg	5:45(w:w)	21-25 g	0.45–0.56 mg	[22]

ISSN: 1743-8977