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Fig. 7 | Particle and Fibre Toxicology

Fig. 7

From: Maternal exposure to nano-titanium dioxide impedes fetal development via endothelial-to-mesenchymal transition in the placental labyrinth in mice

Fig. 7

Schematic diagram of the impacts of TiO2 NPs on embryonic and fetal intrauterine development and the underlying mechanism. Maternal exposure to 100 nm TiO2 NPs resulted in placental accumulation and concomitant transfer to mouse fetuses. TiO2 NP exposure caused EndMT activation in the labyrinth, endothelial dysfunction, disturbance in the placental barrier, and ultimate fetal growth retardance

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