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Fig. 3 | Particle and Fibre Toxicology

Fig. 3

From: Food-grade titanium dioxide and zinc oxide nanoparticles induce toxicity and cardiac damage after oral exposure in rats

Fig. 3

Nanoparticles altered cell morphology. Hearts were fixed, cut into sections and polymerized. Sections were analyzed with an electronic transmission microscope JEOL 1010 equipped with a Hamamatsu camera system. Images are shown at direct magnification between 8000 and 80000x. In control hearts, the integrity of the tissue (Z bands, nucleus, sarcomeric unit and mitochondria) is observed. E171 induced alteration mainly in mitochondria, while ZnO NPs induced the appearance of lysosomes and altered mitochondria). In hearts treated with NPs, the presence of elementary particles was observed

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Particle and Fibre Toxicology

ISSN: 1743-8977

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