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Fig. 5 | Particle and Fibre Toxicology

Fig. 5

From: Food-grade titanium dioxide and zinc oxide nanoparticles induce toxicity and cardiac damage after oral exposure in rats

Fig. 5

Nanoparticles induced apoptosis. Representative images of heart cross-sections of control rats, treated with E171 and ZnO NPs. Apoptotic rate was measured with the TUNEL assay (Green). Muscle fibers were delimited with wheat agglutinin texas red conjugated (WAG-TR) and nuclei were stained with 4', 6-diamidino-2-phenylindole (DAPI) (blue). The graph shows mean ± SD of the percentage of TUNEL-positive cells in 4 fields (40X) of 4 sections from different hearts of each group (n = 16). * p < 0.05 versus control

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