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Table 1 Inflammation in the bronchial airways

From: Human exposure to diesel exhaust induces CYP1A1 expression and AhR activation without a coordinated antioxidant response

 

Air

Diesel

p-value

Bronchial Wash (cells/ml *104)

 Total cells (cells/ml)

6.91 (5.69–9.67)

9.77 (5.52–13.0)

NS

 Neutrophils (cells/ml)

1.18 (0.61–1.88)

2.05 (1.02–3.18)

0.013

 Macrophages (cells/ml)

5.23 (4.5–8.22)

6.59 (4.13–9.75)

NS

 Lymphocytes (cells/ml)

0.24 (0.11–0.38)

0.36 (0.18–0.48)

NS

 Eosinophils (cells/ml)

0.00 (0.00–0.01)

0.01 (0.00–0.04)

NS (0.052)

Submucosal cells (cells/mm2)

 Neutrophils (cells/mm2)

32.30 (17.30–42.90)

72.10 (59.50–82.90)

< 0.001

 Mast cells (cells/mm2)

13.45 (7.53–18.30)

27.20 (18.80–39.10)

0.002

 CD3+ cells (cells/mm2)

31.20 (16.30–51.50)

53.60 (26.70–86.90)

0.007

  1. Data are presented as median and (interquartile ranges). Cells in the bronchial wash are expressed as cell numbers/ml and submucosal cells are expressed as cell numbers/mm2 submucosa area. Comparisons between post air and DE performed using the Wilcoxon-signed-rang-test (n = 16)
  2. All p-values < 0.05 were considered significant, p-values < 0.01 marked bold
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Particle and Fibre Toxicology

ISSN: 1743-8977

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