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Fig. 4 | Particle and Fibre Toxicology

Fig. 4

From: Polystyrene nanobeads exacerbate chronic colitis in mice involving in oxidative stress and hepatic lipid metabolism

Fig. 4

Expression levels of inflammatory factors and MAPK signaling pathway-related proteins in the colon. (A) TNF-α mRNA. (B) IL-10 mRNA. (Data are presented as mean ± SEM, n ≥ 6. One-way ANOVA and Multiple comparisons). (C) Expression of Erk1/2, p-Erk1/2, JNK, p-JNK, p38 and p-p38 proteins. (D) The relative densitometric analysis of p-Erk1/2 and Erk1/2. (E) The relative densitometric analysis of p-JNK and JNK. (F) The relative densitometric analysis of p-p38 and p38. Data are presented as mean ± SD, n = 3. One-way ANOVA and Tukey’s multiple comparison test. The asterisk and pound represents statistically significant difference (*p < 0.05, **p < 0.01 compared to the control group; #p < 0.05, ##p < 0.01 compared to the model group)

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