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Table 2 Scoring criteria of histological analysis

From: Polystyrene nanobeads exacerbate chronic colitis in mice involving in oxidative stress and hepatic lipid metabolism

Liver histology rating indicators

Fat vacuoles

Inflammatory cell infiltration

Hepatocytes are cloudy swelling

Score

Normal

Small vacuoles

Vacuoles in the cytoplasm

Large vacuoles

Normal

A small acount

Major

Vast

Normal

Mild

Moderate

Severe

0

1

2

3

Colon histology rating indicators

Inflammatory infiltration

Crypt injury rate

(CIR)

Score

Normal

infiltrate the base of crypt

infiltrate into the muscularis mucosa

Extensive infiltration of the muscular layer

infiltrate to the submucosa

0

0 < CIR ≤ 1/4

1/4 < CIR ≤ 1/2

1/2 < CIR ≤ 3/4

3/4 < CIR ≤ 1

0

1

2

3

4