Fig. 1From: Comparison of PET tracing and biodistribution between 64Cu-labeled micro-and nano-polystyrene in a murine inhalation modelSchematic of the experiment. 64Cu-DOTA-mPS/nPS was synthesized and characterized using HPLC and radiochemical purity was analyzed using radio-TLC. 64Cu-DOTA-mPS/nPS was intra-tracheally instilled into mice and PET imaging was performed. The organs were extracted at each timepoint and radioactivity was counted in a gamma counter followed by tissue homogenization and ex-vivo TLC analysis to confirm the stability of the labelled products in each organ (mPS = micro polystyrene, nPS = nano polystyrene)Back to article page