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Fig. 3 | Particle and Fibre Toxicology

Fig. 3

From: Comparison of PET tracing and biodistribution between 64Cu-labeled micro-and nano-polystyrene in a murine inhalation model

Fig. 3

(A) Representative PET-CT images of intra-tracheally instilled 64Cu-DOTA-mPS, 64Cu-DOTA-nPS and 64Cu at all time points displaying retention of polystyrene in lungs compared to 64Cu that is rapidly cleared from the lungs post instillation. (B) The graphs represent SUVmax for important organs such as lungs, stomach and liver along with the AUC which is maximum for mPS in lungs and 64Cu in liver. AUC = area under curve; mPS = micro-polystyrene; nPS = nano-polystyrene; L = lungs; S = stomach (*P < 0.05, **P < 0.005, * significance in comparison to 64Cu; * significance in comparison to.64Cu-DOTA-nPS)

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