Skip to main content
Fig. 6 | Particle and Fibre Toxicology

Fig. 6

From: ROS/mtROS promotes TNTs formation via the PI3K/AKT/mTOR pathway to protect against mitochondrial damages in glial cells induced by engineered nanomaterials

Fig. 6

NAC/MitoQ decreases the TNTs formation and mitochondrial transfer induced by nanomaterials. U251 cells were pretreated with 10 mM NAC or 0.2 μM MitoQ for 30 min and then exposed to nanomaterials. A Representative image of TNTs in U251 cells after exposure to nanomaterials. B Statistic analysis of TNTs numbers in U251 cells. C Quantification analysis of mitochondrial transfer in U251 cells. Scale bar = 250 μm. ** and *** indicate P < 0.01 and 0.001 compared with the control group, ## and ### indicate P < 0.01 and 0.001 compared with the respective nanomaterials group (regarding the no intervention nanomaterials group). Scale bar = 25 μm. Date present as mean ± SEM. n = 3

Back to article page