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Fig. 3 | Particle and Fibre Toxicology

Fig. 3

From: Differential pulmonary toxicity and autoantibody formation in genetically distinct mouse strains following combined exposure to silica and diesel exhaust particles

Fig. 3

(a) Representative sections of H&E-stained lung tissue slides (5 μm) of vehicle-, DEP-, silica- and silica + DEP exposed C57BL/6J and NOD/ShiLtJ mice. (b) Pulmonary fibrosis scores of vehicle, DEP, silica and silica + DEP exposed C57BL/6J and NOD/ShiLtJ mice using the modified Ashcroft grading scale [29]. Data are represented as mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 with One-way ANOVA. n = 4 mice/group

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