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Fig. 7 | Particle and Fibre Toxicology

Fig. 7

From: Differential pulmonary toxicity and autoantibody formation in genetically distinct mouse strains following combined exposure to silica and diesel exhaust particles

Fig. 7

Representative Raman microscopic images of unstained deparaffinized lung section of silica + DEP exposed C57BL/6J mouse; (a) Overview of scanned section showing localization of silica particles, indicated by red dots, and DEP particles indicated by yellow dots, obtained through spectrum identification using OMNIC™xi Software and automatic particle analyzer through library matching (library created using Min-U-Sil 5® and NIST2975 reference materials). (b) % of DEP loaded macrophages in DEP and silica + DEP exposed C57BL/6J and NOD/ShiLtJ mice. Data are represented as mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 by One-way ANOVA with Tukey correction for multiple testing. N = 7–8 mice/group

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Particle and Fibre Toxicology

ISSN: 1743-8977

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