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Fig. 6 | Particle and Fibre Toxicology

Fig. 6

From: Acute exposure to polystyrene nanoparticles promotes liver injury by inducing mitochondrial ROS-dependent necroptosis and augmenting macrophage-hepatocyte crosstalk

Fig. 6

PSNPs disrupt the integrity and function of mitochondria in RAW 264.7 cells. (A) The activity of mitochondrial complexes I-V in RAW 264.7 cells treated with or without PSNPs for 4 h. (B) ATP production in RAW 264.7 cells treated with PSNPs for 4 h. (C) Detection of the cell mitochondrial membrane potential after PSNPs treatment for 4 h. Scale bar 50 μm. N.S., no significance. * P < 0.05, ** P < 0.01

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