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Fig. 3 | Particle and Fibre Toxicology

Fig. 3

From: The discovery of regional neurotoxicity-associated metabolic alterations induced by carbon quantum dots in brain of mice using a spatial metabolomics analysis

Fig. 3

The general neurotoxic effects of CQDs in brain of mice. (a) The changes in the body weight of mice; (b) The changes in the organ coefficient of mice brain; (c) Representative histological images represented the whole brain tissue and different regions stained with H&E staining. The yellow arrows indicate bleeding spots, the red arrows indicate inflammatory cell infiltration; (d) Representative histological images represented the whole brain tissue and different regions stained with Nissl staining. The inserted images indicate magnified neurons with lighter Nissl bodies staining, vacuolar degeneration (red arrow) and blurry edges (yellow arrow) after CQDs exposure. Olfactory bulb (OB), Cortex (COR), Hippocampus (HIP), Corpus Striatum (CS), Midbrain (MB), Cerebellum (CE), Nucleus Accumbens (NAcc), Lateral Habenula Nucleus (LHB) and Zona Incerta (ZI)

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Particle and Fibre Toxicology

ISSN: 1743-8977

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