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Fig. 5 | Particle and Fibre Toxicology

Fig. 5

From: The discovery of regional neurotoxicity-associated metabolic alterations induced by carbon quantum dots in brain of mice using a spatial metabolomics analysis

Fig. 5

In situ visualization of critical metabolites and metabolic enzymes in biosynthesis of unsaturated fatty acids changed by CQDs in brain of mice. (a) MS images and levels of fatty acids in different regions of brain tissue section; Representative IHC staining showed the expression of ACOT2 (b, c) and BAAT (d, e) in different regions of brain tissue section and their IHC scores. Olfactory bulb (OB), Cortex (COR), Hippocampus (HIP), Corpus Striatum (CS), Midbrain (MB), Cerebellum (CE), Nucleus Accumbens (NAcc), Lateral Habenula Nucleus (LHB) and Zona Incerta (ZI). Data are showed as mean ± SD of three independent experiments. (*P < 0.05, **P < 0.01, ***P < 0.001)

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Particle and Fibre Toxicology

ISSN: 1743-8977

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