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Table 4 Dosimetry of Cu NPs in the whole blood, lung and placenta

From: Effects of prenatal inhalation exposure to copper nanoparticles on murine dams and offspring

Experimental group Cu Concentration, Mean ± SE  
Whole blood, μg/L Lungs, mg/kg Placenta, mg/kg Fetus (GD19), mg/kg
Adult females PND 0 PND 50 PND 0 PND 50   
Exposed Pregnant 1400 ± 91.7### 644 ± 7.0 85.9 ± 3.9***, ### 28.5 ± 3.4**, ## 19.9 ± 1.8 11.6 ± 0.3
Non-Pregnant 737 ± 26.4 669 ± 20.7 54.4 ± 2.8*** 20.0 ± 0.6*** -- --
Shams Pregnant 1450 ± 18.3 ND 23.4 ± 4.1 12.8 ± 1.0 17.6 ± 1.6 11.1 ± 0.5
Non-Pregnant 704 ± 13.2 ND 13.0 ± 1.2 11.8 ± 0.4 -- --
Pups
Exposed -- 600 ± 18.9 ND ND  
Shams -- 655 ± 30.0 ND ND
  1. ND not determined
  2. ### p < 0.001, ## p < 0.01 significant difference between pregnant and non-pregnant mice
  3. ***p < 0.001, **p < 0.01 significant difference between exposed and control counterparts