Table 3 Summary of the AOP of digestive system
Sequence | Type | Event ID | Title | Short name |
|---|---|---|---|---|
1 | MIE | 1115 | ROS generation | Increased, Reactive oxygen species |
2 | MIE | 151 | Inflammatory pathways Activation | Inflammatory pathways Activation |
3 | KE | 1392 | Oxidative stress | Oxidative stress |
4 | KE | 1995 | Abnormal lipid metabolism | Abnormal lipid metabolism |
5 | KE | 1497 | Infiltration of inflammatory cells | Infiltration of inflammatory cells |
6 | KE | 149 | Inflammatory response | Increase, Inflammation |
7 | KE | 1496 | Secretion of inflammatory factors | Increased proinflammatory mediators |
8 | KE | 459 | Liver Steatosis | Increased, Liver Steatosis |
9 | KE | 1954 | Gut microbiota alteration | Gut dysbiosis |
10 | KE | 1549 | Liver injury | Liver injury |
11 | KE | 1997 | Colonic epithelial lesions | Colon epithelial lesions |
12 | AO | 1996 | Increased morbidity and mortality of digestive disease | Increased morbidity and mortality of digestive disease |